Progress in HIV⁃related nervous system diseases

Abstract

Since combination antiretroviral therapy (cART) appeared, the epidemiology and spectrum of human immunodeficiency virus (HIV)⁃related nervous system diseases have changed significantly. HIV⁃related neurological syndromes are more common, including primary infection, opportunistic infection, immune reconstitution inflammatory syndrome, antiretroviral⁃drugs related neurotoxic effects, etc; and aging⁃related diseases, including HIV⁃associated neurocognitive disorder (HAND), HIV⁃related cerebrovascular diseases, and HIV⁃related peripheral neuropathy. This article reviews the research progress of HIV⁃related nervous system diseases, which is helpful for clinicians to recognize early, diagnose and treat in time.

Keywords

• hiv
• nervous system diseases
• antiviral agents
• retroviridae
• review