Revista da Sociedade Brasileira de Medicina Tropical (Oct 2015)

Molecular characterization of group A rotavirus before and after the introduction of vaccines in Brazil

  • Tâmera Nunes Vieira Almeida,
  • Fabíola Souza Fiaccadori,
  • Menira Souza,
  • Ana Maria Tavares Borges,
  • Divina das Dôres de Paula Cardoso

DOI
https://doi.org/10.1590/0037-8682-0023-2015
Journal volume & issue
Vol. 48, no. 5
pp. 599 – 602

Abstract

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ABSTRACTINTRODUCTION:In this study, the molecular characteristics of group A rotavirus (RVA) were compared in samples obtained before and after RVA vaccine-introduction in Brazil.METHODS:Eighty samples were screened for the presence of RVA. Positive samples were molecularly analyzed.RESULTS:RVA positivity was 16.9%, with a predominance of G2P[4]. Periods: pre-vaccination: predominance of IId (G1), IId (G2) lineages, and I1 and E1 genotypes; post-vaccination: predominance of Ib (G1), IIa, and IIc (G2) lineages and I2 and E2 genotypes.CONCLUSIONS:Although changes in RVA-circulation pattern were observed in the post-vaccination period, it could not be attributed to vaccination process.

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