Combination of Selective PARP3 and PARP16 Inhibitory Analogues of Latonduine A Corrects F508del-CFTR Trafficking

• Ryan M. Centko,
• Graeme W. Carlile,
• Isabel Barne,
• Brian O. Patrick,
• Polina Blagojevic,
• David Y. Thomas,
• Raymond J. Andersen

Affiliations

Ryan M. Centko

†Department of Chemistry, University of British Columbia, Vancouver, British Columbia, Canada

Graeme W. Carlile

Departments of Biochemistry and Human Genetics and The Cystic Fibrosis Translational Research Centre, McGill University, Montréal, Québec, Canada

Isabel Barne

†Department of Chemistry, University of British Columbia, Vancouver, British Columbia, Canada

Brian O. Patrick

†Department of Chemistry, University of British Columbia, Vancouver, British Columbia, Canada

Polina Blagojevic

†Department of Chemistry, University of British Columbia, Vancouver, British Columbia, Canada

David Y. Thomas

Departments of Biochemistry and Human Genetics and The Cystic Fibrosis Translational Research Centre, McGill University, Montréal, Québec, Canada

Raymond J. Andersen

†Department of Chemistry, University of British Columbia, Vancouver, British Columbia, Canada