Case Reports in Gastroenterology (Oct 2011)

Multiple Gastric Carcinomas Associated with Potter Type III Cystic Disease

  • Kenji Mimatsu,
  • Takatsugu Oida,
  • Atsushi Kawasaki,
  • Hisao Kano,
  • Kazutoshi Kida,
  • Nobutada Fukino,
  • Youichi Kuboi,
  • Sadao Amano

DOI
https://doi.org/10.1159/000329179
Journal volume & issue
Vol. 5, no. 3
pp. 590 – 596

Abstract

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We report a case of multiple gastric carcinomas associated with Potter type III cystic disease of the liver, mesenterium and kidney. A 65-year-old man with chronic renal failure due to polycystic kidneys and under hemodialysis treatment 3 times a week for 2 years was admitted to our hospital because of anemia. He stated that his sister had suffered from polycystic kidney disease. Gastrointestinal fiberscopy showed two lesions in the lesser curvature in the lower portion of the stomach, and histopathological analysis of the gastric tumor biopsies revealed that one of the tumors was a papillary adenocarcinoma and the other a poorly differentiated adenocarcinoma. Helicobacter pylori infection was not detected in the stomach mucosa. Abdominal computed tomography scan revealed polycystic lesions in the liver, mesenterium and both kidneys. These imaging findings and family history suggested that the patient suffered from multiple gastric carcinomas associated with Potter type III cystic disease of the liver, mesenterium and kidney. Reports on the association of malignant neoplasm with Potter type III cystic disease are extremely rare. Especially, no case of the association of gastric carcinoma with Potter type III cystic disease of the liver and kidney has been described previously. This is a first report of the association of gastric carcinoma with Potter type III cystic disease. We also review reports of other malignant neoplasms associated with polycystic disease.

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