Synthesis of some novel annulated pyrido[2,3-d]pyrimidines via stereoselective intramolecular hetero Diels–Alder reactions of 1-oxa-1,3-butadienes

Abstract

Some novel annulated pyrido[2,3-d]pyrimidines 6 and 7 were synthesized stereoselectively by intramolecular hetero Diels–Alder reactions involving 1-oxa-1,3-butadienes.

Keywords

• β-halo aldehydes
• hetero Diels–Alder reaction
• 1-oxa-1,3-butadiene
• pyrido[2,3-d]pyrimidines
• uracil