Nature Communications (May 2021)

Immune response to SARS-CoV-2 variants of concern in vaccinated individuals

  • Matthias Becker,
  • Alex Dulovic,
  • Daniel Junker,
  • Natalia Ruetalo,
  • Philipp D. Kaiser,
  • Yudi T. Pinilla,
  • Constanze Heinzel,
  • Julia Haering,
  • Bjoern Traenkle,
  • Teresa R. Wagner,
  • Mirjam Layer,
  • Martin Mehrlaender,
  • Valbona Mirakaj,
  • Jana Held,
  • Hannes Planatscher,
  • Katja Schenke-Layland,
  • Gérard Krause,
  • Monika Strengert,
  • Tamam Bakchoul,
  • Karina Althaus,
  • Rolf Fendel,
  • Andrea Kreidenweiss,
  • Michael Koeppen,
  • Ulrich Rothbauer,
  • Michael Schindler,
  • Nicole Schneiderhan-Marra

DOI
https://doi.org/10.1038/s41467-021-23473-6
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 8

Abstract

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Here, the authors characterize the antibody response from vaccinated (Pfizer BNT-162b2), infected and uninfected individuals against emerging variants of concern of SARS-CoV-2, finding reduced neutralization of a South African isolate. High IgG titers in the saliva of vaccinees suggest that transmission may be reduced.