Nature Communications (May 2021)
Immune response to SARS-CoV-2 variants of concern in vaccinated individuals
- Matthias Becker,
- Alex Dulovic,
- Daniel Junker,
- Natalia Ruetalo,
- Philipp D. Kaiser,
- Yudi T. Pinilla,
- Constanze Heinzel,
- Julia Haering,
- Bjoern Traenkle,
- Teresa R. Wagner,
- Mirjam Layer,
- Martin Mehrlaender,
- Valbona Mirakaj,
- Jana Held,
- Hannes Planatscher,
- Katja Schenke-Layland,
- Gérard Krause,
- Monika Strengert,
- Tamam Bakchoul,
- Karina Althaus,
- Rolf Fendel,
- Andrea Kreidenweiss,
- Michael Koeppen,
- Ulrich Rothbauer,
- Michael Schindler,
- Nicole Schneiderhan-Marra
Affiliations
- Matthias Becker
- NMI Natural and Medical Sciences Institute at the University of Tübingen
- Alex Dulovic
- NMI Natural and Medical Sciences Institute at the University of Tübingen
- Daniel Junker
- NMI Natural and Medical Sciences Institute at the University of Tübingen
- Natalia Ruetalo
- Institute for Medical Virology and Epidemiology, University Hospital Tübingen
- Philipp D. Kaiser
- NMI Natural and Medical Sciences Institute at the University of Tübingen
- Yudi T. Pinilla
- Institute of Tropical Medicine, University of Tübingen
- Constanze Heinzel
- Institute of Tropical Medicine, University of Tübingen
- Julia Haering
- NMI Natural and Medical Sciences Institute at the University of Tübingen
- Bjoern Traenkle
- NMI Natural and Medical Sciences Institute at the University of Tübingen
- Teresa R. Wagner
- NMI Natural and Medical Sciences Institute at the University of Tübingen
- Mirjam Layer
- Institute for Medical Virology and Epidemiology, University Hospital Tübingen
- Martin Mehrlaender
- Department of Anaesthesiology and Intensive Care Medicine, University Hospital Tübingen
- Valbona Mirakaj
- Department of Anaesthesiology and Intensive Care Medicine, University Hospital Tübingen
- Jana Held
- Institute of Tropical Medicine, University of Tübingen
- Hannes Planatscher
- Signatope GmbH
- Katja Schenke-Layland
- NMI Natural and Medical Sciences Institute at the University of Tübingen
- Gérard Krause
- Helmholtz Centre for Infection Research
- Monika Strengert
- Helmholtz Centre for Infection Research
- Tamam Bakchoul
- Institute for Clinical and Experimental Transfusion Medicine, University Hospital Tübingen
- Karina Althaus
- Institute for Clinical and Experimental Transfusion Medicine, University Hospital Tübingen
- Rolf Fendel
- Institute of Tropical Medicine, University of Tübingen
- Andrea Kreidenweiss
- Institute of Tropical Medicine, University of Tübingen
- Michael Koeppen
- Department of Anaesthesiology and Intensive Care Medicine, University Hospital Tübingen
- Ulrich Rothbauer
- NMI Natural and Medical Sciences Institute at the University of Tübingen
- Michael Schindler
- Institute for Medical Virology and Epidemiology, University Hospital Tübingen
- Nicole Schneiderhan-Marra
- NMI Natural and Medical Sciences Institute at the University of Tübingen
- DOI
- https://doi.org/10.1038/s41467-021-23473-6
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 8
Abstract
Here, the authors characterize the antibody response from vaccinated (Pfizer BNT-162b2), infected and uninfected individuals against emerging variants of concern of SARS-CoV-2, finding reduced neutralization of a South African isolate. High IgG titers in the saliva of vaccinees suggest that transmission may be reduced.
