The Variability of Clinical Implications of Burkitt’s Lymphoma in Children

Abstract

There are about 11–15% of non-Hodgkin's lymphomas, among all cases of hematological cancer, which derive from B and T cell lines, in children. Non-Hodgkin's lymphoma from the differentiated B cells is the most frequent clinical entity of lymphomas in children; Burkitt's lymphoma is the most common type of non-Hodgkin's lymphoma. The proliferative capacity of Burkitt's lymphoma is one of the highest in pediatric oncology: the potential time of tumour load duplication may be about 12 hours; Burkitt's lymphomas are marked by the highest malignancy and different systemic symptoms. Therefore, pediatricians of different specialities should have oncologic vigilance; clear and quick diacritic and therapeutic management should also be established by the pediatric oncologist or hematologist. Two clinical cases of B cell Burkitt's lymphoma in children of different age, and the initial status of a patient, are described in this article.

Keywords

• children
• non-hodgkin's lymphomas
• burkitt's lymphoma
• clinical presentation