Nature Communications (Jun 2020)

Sequential modification of bacterial chemoreceptors is key for achieving both accurate adaptation and high gain

  • Bernardo A. Mello,
  • Anderson B. Beserra,
  • Yuhai Tu

DOI
https://doi.org/10.1038/s41467-020-16644-4
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 10

Abstract

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Bacterial chemoreceptors have multiple methylation sites, but whether the order of methylation matters is unclear. Here, the authors show that sequentially ordered methylation is critical for perfect adaptation and for attenuating the trade-off between accurate adaptation and high response gain.