Nature Communications (Apr 2020)

Perturbing proteomes at single residue resolution using base editing

  • Philippe C. Després,
  • Alexandre K. Dubé,
  • Motoaki Seki,
  • Nozomu Yachie,
  • Christian R. Landry

DOI
https://doi.org/10.1038/s41467-020-15796-7
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 13

Abstract

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Base editors allow for the precise modification of genes. Here the authors use Target-AID to systematically test 17,000 sites across the yeast genome.