Selenium contents, speciation and bioaccessibility of Se-enriched rice grains from Chinese markets

Abstract

Diet intake accounts for >90% of selenium (Se) exposure in humans, with rice being the main source of Se intake for >60% of the Chinese population. In this study, 48 rice grain samples labeled Se-enriched were obtained from 22 major rice producing areas in China through online sources. Their total Se contents, Se speciation, and Se bioaccessibility were evaluated to provide a holistic view of Se-enriched rice in the market. The total Se contents were 0.006–0.951 ​μg ​g−1 (average 0.249 ​μg ​g−1), which showed great regional variations, with 73% of the samples satisfying the Se-enriched standard based on GB/T22499-2008 (0.04–0.30 ​mg ​kg−1). Over 80% of Se in the rice samples was organic Se species including selenomethionine, selenocysteine and methylselenocysteine, with selenomethionine being the main Se species, accounting for 61–98%. Based on a modified physiologically-based extraction test (MPBET), the Se bioaccessibility in 33 selected samples was 8.05–49.6% (28.6%) in the gastric phase and 18.1–117% (82.5%) in the intestinal phase. Further, Se bioaccessibility was positively correlated with organic Se (r ​= ​0.89–0.93), but not with inorganic Se (selenite and selenate), suggesting that Se bioaccessibility depended on organic Se in these rice grains. The data call for re-evaluation of Se-enriched rice in the market. Further, the potential risk of long-term consumption of Se-enriched rice in the market towards human health should be studied.

Keywords

• Human health
• Regional variation
• Se-enriched rice
• Modified physiologically-based extraction test
• Organic Se
• Selenium exposure