Data on the anti-tumor effects of Selaginella tamariscina extract and amentoflavone combined with doxorubicin in mice
Chang Gun Lee,
Eun Ha Lee,
Cheol-Ho Pan,
Kyungsu Kang,
Ki-Jong Rhee
Affiliations
Chang Gun Lee
Department of Biomedical Laboratory Science, College of Health Sciences, Yonsei University, Wonju 26493, Republic of Korea
Eun Ha Lee
Systems Biotechnology Research Center, Korea Institute of Science and Technology, Gangneung 25451, Republic of Korea
Cheol-Ho Pan
Systems Biotechnology Research Center, Korea Institute of Science and Technology, Gangneung 25451, Republic of Korea; Department of Biological Chemistry, University of Science and Technology (UST), Daejeon 34113, Republic of Korea
Kyungsu Kang
Systems Biotechnology Research Center, Korea Institute of Science and Technology, Gangneung 25451, Republic of Korea; Department of Biological Chemistry, University of Science and Technology (UST), Daejeon 34113, Republic of Korea; Corresponding author at: Systems Biotechnology Research Center, Korea Institute of Science and Technology, Gangneung 25451, Republic of Korea.
Ki-Jong Rhee
Department of Biomedical Laboratory Science, College of Health Sciences, Yonsei University, Wonju 26493, Republic of Korea; Corresponding author.
Here, we report animal experimental data associated with the article entitled “AKR1B10-inhibitory Selaginella tamariscina extract and amentoflavone decrease the growth of A549 human lung cancer cells in vitro and in vivo“ (Jung et al., 2017) [1]. We tested the synergistic anti-tumor effects of Selaginella tamariscina extract and amentoflavone combined with doxorubicin hydrochloride in a nude mouse xenograft model of A549 human lung cancer cells. In our experiment, Selaginella tamariscina extract and amentoflavone were administered orally; and doxorubicin hydrochloride was injected intraperitoneally. We expect our preliminary data will be helpful to the development of the anticancer agent using Selaginella tamariscina extract or amentoflavone. Keywords: Amentoflavone, Anti-tumor, Doxorubicin, Selaginella tamariscina
