Are Hematological Parameters Useful in Assessing Disease Activity in Chronic Otitis Media?

Abstract

Aim:To investigate the role of hematological parameters in assessing disease activity of chronic otitis media (COM).Methods:Patients who underwent surgery for COM between 2014 and 2018 were examined retrospectively. The patients were divided into active and inactive COM groups. Active group was divided into cholesteatoma, granulation tissue, and cholesteatoma + granulation tissue subgroups. Inactive group was divided into tympanosclerosis and normal middle ear mucosa subgroups. Preoperative complete blood count parameters were examined retrospectively. Neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and mean platelet volume (MPV) in active and inactive groups and also the values in subgroups of each group were compared.Results:Our study contained 1126 patients. There were 558 (49.55%) male, 568 (50.45%) female patients. The mean age was 31±14.93 (7-74) years. Active and inactive groups consisted of 329 (29.22%) and 797 (70.78%) patients, respectively. There was no significant difference between active and inactive COM groups in terms of NLR (p=0.234), PLR (p=0.733) and MPV (p=0.992). There was no significant difference among subgroups of active and inactive groups (p>0.05). Receiver operating characteristic curve analysis for NLR, PLR and MPV in the groups revealed no cut-off value for differentiating any group from another (p>0.05).Conclusion:NLR, PLR, and MPV values do not have any significant value in the assessment of disease activity of COM.

Keywords

• chronic otitis media
• disease activity
• hematological parameter