Elderly male patient presenting with jaundice and cholangitis brings an unexpected histopathological finding, case report
Gergana Nenova,
Dietrich A. Ruess,
Sophia Chikhladze,
Heiko Becker,
Sylvia Timme-Bronsert,
Uwe Wittel
Affiliations
Gergana Nenova
Department of General and Visceral Surgery, University of Freiburg Medical Center, Freiburg, Germany; Corresponding author.
Dietrich A. Ruess
Department of General and Visceral Surgery, University of Freiburg Medical Center, Freiburg, Germany
Sophia Chikhladze
Department of General and Visceral Surgery, University of Freiburg Medical Center, Freiburg, Germany
Heiko Becker
Department of Hematology and Oncology, University of Freiburg Medical Center, Freiburg, Germany; Comprehensive Cancer Center Freiburg (CCCF), University of Freiburg Medical Center, Freiburg, Germany
Sylvia Timme-Bronsert
Institute for Surgical Pathology, University of Freiburg Medical Center, Freiburg, Germany
Uwe Wittel
Department of General and Visceral Surgery, University of Freiburg Medical Center, Freiburg, Germany
In this report, we present a case of the first-time manifestation of Langerhans cell histiocytosis in the biliary tract of a 79-year-old male patient. Cholangiocarcinoma was the suspected diagnosis, based on the patient's painless jaundice. The postoperative histological findings revealed a primary, single-system, unifocal Langerhans cell histiocytosis of the biliary tract, without the patient having any other typical clinical manifestations, e.g., of the skin or lungs. Neither the primary manifestation nor the patient's age fully aligns with current knowledge of Langerhans cell histiocytosis.
