Anti-MOG associated myelitis

Abstract

There is now increasing evidence that demyelinating disease with anti-myelin oligodendrocyte glycoprotein (anti-MOG) antibodies is an independent nosological unit. The paper describes a clinical case of anti-MOG associated myelitis at the CI-TXlevel. Differential diagnosis was made between multiple sclerosis, Devic's myelitis optica, and idiopathic transverse myelitis. The clinical, morphopathological, and diagnostic features of anti-MOG associated myelitis are discussed. There are new diagnostic criteria for neuromyelitis optica spectrum diseases (NMOSD), as well as red flags, in the absence of which the diagnosis of NMOSD can be established as a diagnosis of exclusion.

Keywords

• anti-mog associated myelitis
• anti-mog antibodies
• anti-aquaporin-4 antibodies
• transverse myelitis
• multiple sclerosis
• devic's myelitis optica
• neuromyelitis optica spectrum diseases