Journal of Multidisciplinary Healthcare (Feb 2024)
The Impact of Nursing Interventions on the Treatment Outcomes of Renal Cell Carcinoma with Postoperative Interleukin-2 and Recombinant Human Interferon
Abstract
Li Guo,1 Li-Qin Zhao,2 Jin-Yu Chen,2 Ming Li2 1Third Department of General Surgery (Breast Armor Surgery), Ezhou Central Hospital, Ezhou City, 436000, People’s Republic of China; 2Department of Oncology, Ezhou Central Hospital, Ezhou City, 436000, People’s Republic of ChinaCorrespondence: Ming Li, Department of Oncology, Ezhou Central Hospital, No. 9 Wenxing Road, Echeng District, Ezhou City, Hubei Province, 436000, People’s Republic of China, Tel + 86-15969693217, Email [email protected]: This study investigates the impact of nursing interventions on treatment outcomes and adverse reaction rates in renal cell carcinoma (RCC) patients treated postoperatively with Interleukin-2 and recombinant human Interferon.Methods: In a retrospective analysis of 90 RCC patients, 43 received standard care (control group), while 47 received additional nursing interventions (intervention group), including psychological care, vital signs monitoring, dietary care, adverse reaction management, and post-discharge care. Patients with concurrent major diseases or other malignancies were excluded. Key assessments included clinical symptom improvement, treatment efficacy, and postoperative adverse reactions.Results: Among the 90 participants, no significant demographic differences were found between the two groups. The intervention group showed significant improvements in fever resolution, leukocyte normalization, and shorter hospital stays. The overall treatment effectiveness was similar in both groups (90.7% in the intervention group vs 91.5% in the control group). However, the intervention group experienced significantly fewer postoperative adverse reactions, including fever, gastrointestinal symptoms, bone marrow suppression, and neurological abnormalities (6.3% vs 23.2%).Conclusion: The study suggests that nursing interventions can improve treatment outcomes by reducing postoperative adverse reactions in RCC patients receiving postoperative Interleukin-2 and recombinant human Interferon. The overall effectiveness of treatment and care was comparable between the groups. Further extensive studies are needed to confirm these findings and fully understand the impact of nursing interventions on RCC patient outcomes.Keywords: renal cell carcinoma, interleukin-2, recombinant human interferon, nursing interventions, treatment outcomes, adverse reactions
