Determination of thimerosal in non-adsorbed immunobiological preparations by cold vapor atomic absorption spectroscopy (CV AAS) for the ions of mercury. Part 1: method development and evaluation of statistical significance of differences in the results of mercury ions determination by colorimetric method and cold vapor atomic absorption spectroscopy method

Abstract

The article describes development of methods of quantitative determination of thimerosal in non-adsorbed immunobiological preparations by cold vapor atomic absorption spectroscopy as well as an estimation of the statistical significance of differences in the results determination of thimerosal conventional colorimetric method in combination with dithizone and CV AAS using one-way analysis of variance with Fisher’s exact test (F-test).

Keywords

• thimerosal
• quantitative evaluation
• assessment atomic absorption spectroscopy
• statistical significance of differences
• мертиолят
• количественная оценка
• атомно-абсобционная спектроскопия холодного пара
• статистически значимые различия