Preserved cognitive functions with age are determined by domain-dependent shifts in network responsivity

Dávid Samu; Karen L. Campbell; Kamen A. Tsvetanov; Meredith A. Shafto; Cam-CAN consortium; Lorraine K. Tyler

doi:10.1038/ncomms14743

Nature Communications (May 2017)

Preserved cognitive functions with age are determined by domain-dependent shifts in network responsivity

Dávid Samu,
Karen L. Campbell,
Kamen A. Tsvetanov,
Meredith A. Shafto,
Cam-CAN consortium,
Lorraine K. Tyler

Affiliations

Dávid Samu: Department of Psychology, University of Cambridge
Karen L. Campbell: Cambridge Centre for Ageing and Neuroscience (Cam-CAN), University of Cambridge and MRC Cognition and Brain Sciences Unit
Kamen A. Tsvetanov: Department of Psychology, University of Cambridge
Meredith A. Shafto: Department of Psychology, University of Cambridge
Cam-CAN consortium
Lorraine K. Tyler: Department of Psychology, University of Cambridge

DOI: https://doi.org/10.1038/ncomms14743
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 14

Abstract

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Cognitive abilities change with age, but why some decline and some do not is not clear. Here, the authors use data from the Cam-CAN cohort to show that distributed, multi-component brain responsivity and default-mode deactivation supports and characterizes preserved cognition across the adult lifespan.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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