Nature Communications (Jun 2017)

A molecular portrait of microsatellite instability across multiple cancers

  • Isidro Cortes-Ciriano,
  • Sejoon Lee,
  • Woong-Yang Park,
  • Tae-Min Kim,
  • Peter J. Park

DOI
https://doi.org/10.1038/ncomms15180
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 12

Abstract

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Some cancers with DNA mismatch repair deficiency display microsatellite instability. Here the authors analyse twenty three cancer types at the exome and whole-genome level, and identify loci with recurrent microsatellite instability that could be used to identify patients who would benefit from immunotherapy.