Frontiers in Nutrition (Nov 2022)

Association between malnutrition and contrast-associated acute kidney injury in congestive heart failure patients following coronary angiography

  • Ming Ying,
  • Ming Ying,
  • Junqing Yang,
  • Zhidong Huang,
  • Zhidong Huang,
  • Yihang Ling,
  • Yihang Ling,
  • Yihang Ling,
  • Bo Wang,
  • Bo Wang,
  • Haozhang Huang,
  • Haozhang Huang,
  • Haozhang Huang,
  • Qiang Li,
  • Qiang Li,
  • Jin Liu,
  • Jin Liu,
  • Yong Liu,
  • Yong Liu,
  • Zhujun Chen,
  • Zhujun Chen

DOI
https://doi.org/10.3389/fnut.2022.937237
Journal volume & issue
Vol. 9

Abstract

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BackgroundPrevious studies have shown that malnutrition is very common in patients with congestive heart failure (CHF) and is closely related to the occurrence of acute kidney injury. However, the relationship between malnutrition and contrast-associated acute kidney injury (CA-AKI) is unclear.Method and resultsWe obtained data from 842 patients who were diagnosed with CHF following coronary angiography (CAG) or percutaneous coronary angiography (PCI) and had follow-up information from January 2013 to February 2016. The patients were divided into 3 groups according to the Controlling Nutritional Status Score before CAG or PCI procedure (Group 1: Normal; Group 2: Mild Malnutrition; Group 3: Moderate to Severe Malnutrition). The main endpoint was CA-AKI. Univariate and multivariable logistic regression analyses were performed. 556 (60.0%) patients suffered from malnutrition before CAG or PCI. During a median follow-up of 2.1 years, A total of 49 (5.82%) patients developed CA-AKI. Additionally, 5 (1.75%), 26 (6.27%) and 18 (12.77%) events were documented in patients with normal, mild and moderate or severe malnutrition, respectively (p < 0.01). In multivariable-adjusted models, patients with malnutrition showed a significantly higher incidence of CA-AKI than those in the normal group.ConclusionMalnutrition is an independent risk factor for CA-AKI in CHF patients following CAG.

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