Genetic and neuronal mechanisms governing the sex-specific interaction between sleep and sexual behaviors in Drosophila

Dandan Chen; Divya Sitaraman; Nan Chen; Xin Jin; Caihong Han; Jie Chen; Mengshi Sun; Bruce S. Baker; Michael N. Nitabach; Yufeng Pan

doi:10.1038/s41467-017-00087-5

Nature Communications (Jul 2017)

Genetic and neuronal mechanisms governing the sex-specific interaction between sleep and sexual behaviors in Drosophila

Dandan Chen,
Divya Sitaraman,
Nan Chen,
Xin Jin,
Caihong Han,
Jie Chen,
Mengshi Sun,
Bruce S. Baker,
Michael N. Nitabach,
Yufeng Pan

Affiliations

Dandan Chen: The Key Laboratory of Developmental Genes and Human Disease, Institute of Life Sciences, Southeast University
Divya Sitaraman: Janelia Research Campus, Howard Hughes Medical Institute
Nan Chen: Janelia Research Campus, Howard Hughes Medical Institute
Xin Jin: Department of Cellular and Molecular Physiology, Yale School of Medicine
Caihong Han: The Key Laboratory of Developmental Genes and Human Disease, Institute of Life Sciences, Southeast University
Jie Chen: The Key Laboratory of Developmental Genes and Human Disease, Institute of Life Sciences, Southeast University
Mengshi Sun: The Key Laboratory of Developmental Genes and Human Disease, Institute of Life Sciences, Southeast University
Bruce S. Baker: Janelia Research Campus, Howard Hughes Medical Institute
Michael N. Nitabach: Janelia Research Campus, Howard Hughes Medical Institute
Yufeng Pan: The Key Laboratory of Developmental Genes and Human Disease, Institute of Life Sciences, Southeast University

DOI: https://doi.org/10.1038/s41467-017-00087-5
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 14

Abstract

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Genes and circuits involved in sleep and sexual arousal have been extensively studied in Drosophila. Here the authors identify the sex determination genes fruitless and doublesex, and a sex-specific P1-DN1 neuronal feedback that governs the interaction between these competing behaviors

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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