Chlamydia psittaci: A zoonotic pathogen causing avian chlamydiosis and psittacosis
Jiewen Wang,
Buwei Wang,
Jian Xiao,
Yuqing Chen,
Chuan Wang
Affiliations
Jiewen Wang
Institute of Pathogenic Biology, School of Basic Medicine, Hengyang Medical College, University of South China; Hunan Provincial Key Laboratory for Special Pathogens Prevention and Control, Hengyang, Hunan, China
Buwei Wang
Institute of Pathogenic Biology, School of Basic Medicine, Hengyang Medical College, University of South China; Hunan Provincial Key Laboratory for Special Pathogens Prevention and Control, Hengyang, Hunan, China
Jian Xiao
The Affiliated Nanhua Hospital, Department of laboratory medicine, Hengyang Medical School, University of South China, Hengyang, Hunan, China
Yuqing Chen
Clinical Microbiology Laboratory, Xiangtan Central Hospital, Xiangtan, Hunan, China
Chuan Wang
Institute of Pathogenic Biology, School of Basic Medicine, Hengyang Medical College, University of South China; Hunan Provincial Key Laboratory for Special Pathogens Prevention and Control, Hengyang, Hunan, China
Chlamydia psittaci is an obligate intracellular gram-negative bacterium with a unique biphasic developmental cycle. It is a zoonotic pathogen with a wide range of hosts and can cause avian chlamydiosis in birds and psittacosis in humans. The pathogen is transmitted mainly through horizontal transmission between birds. Cross-species transmission sometimes occurs and human-to-human transmission has recently been confirmed. This review provides an updated overview of C. psittaci from the perspective of both avian chlamydiosis and psittacosis. We include the aspects of genotype, host-pathogen interaction, transmission, epidemiology, detection and diagnosis, clinical manifestation, management, and prevention, aiming to provide a basic understanding of C. psittaci and offer fresh insights focused on zoonosis and cross-species transmission.
