Squamous cell carcinoma arising in a partially ruptured giant mature cystic teratoma: A case report

Abstract

Mature cystic teratomas are the most common ovarian germ cell tumors and represent 70% of the benign ovarian tumors occurring in women under age 30. In less than 2% of cases, these tumors can transform into malignancies. Squamous cell carcinoma arises most frequently from these tumors (in 80% of cases). Intra-peritoneal rupture accounts for approximately 1%-2% of cystic teratoma complications with most ruptures occurring either intraoperatively during laparoscopic surgery or due to trauma. This case report describes the common presentation, imaging, and pathologic findings of a mature cystic teratoma with 2 uncommon associated complications. Keywords: Mature ovarian teratoma, Ovarian germ cell tumor, Ovarian squamous cell cancer, Rupture, Malignant transformation