Frontiers in Oncology (Jul 2021)

Induction Strategy for Locally Advanced Thymoma

  • Yang Zhang,
  • Zongjuan Li,
  • Yixing Chen,
  • Lijie Tan,
  • Zhaochong Zeng,
  • Jianyong Ding,
  • Shisuo Du

DOI
https://doi.org/10.3389/fonc.2021.704220
Journal volume & issue
Vol. 11

Abstract

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Surgery remains cornerstone for the management of thymoma. Complete surgical resection (R0), is recognized as the constant and significant factor for prognosis. However, in locally advanced (Masaoka-Koga stages III-IVa) thymomas, achieving R0 resection remains challenging due to local-regional invasion of the disease. Induction treatment, with the aim of reducing bulky tumor mass, offers new strategy to facilitate totally surgical resection. Herein, we reviewed recent progress and provided a comprehensive overview of induction strategy in locally advance thymoma.

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