The Chemical and Products Database v4.0, an updated resource supporting chemical exposure evaluations

Sakshi Handa; Kristin K. Isaacs; Jonathan T. Wall; Allison Larger; Scott Burns; Lauren E. Koval; Kenta Baron-Furuyama; Colleen M. Elonen; David Lyons; Kathie L. Dionisio; M. Beth Horton; Katherine A. Phillips

doi:10.1038/s41597-025-05240-0

Scientific Data (Jun 2025)

The Chemical and Products Database v4.0, an updated resource supporting chemical exposure evaluations

Sakshi Handa,
Kristin K. Isaacs,
Jonathan T. Wall,
Allison Larger,
Scott Burns,
Lauren E. Koval,
Kenta Baron-Furuyama,
Colleen M. Elonen,
David Lyons,
Kathie L. Dionisio,
M. Beth Horton,
Katherine A. Phillips

Affiliations

Sakshi Handa: U.S. Environmental Protection Agency, Office of Research and Development, Center for Computational Toxicology and Exposure
Kristin K. Isaacs: U.S. Environmental Protection Agency, Office of Research and Development, Center for Computational Toxicology and Exposure
Jonathan T. Wall: U.S. Environmental Protection Agency, Office of Research and Development, Center for Computational Toxicology and Exposure
Allison Larger: General Dynamics Information Technology
Scott Burns: Oak Ridge Associated Universities
Lauren E. Koval: Oak Ridge Associated Universities
Kenta Baron-Furuyama: U.S. Environmental Protection Agency, Office of Research and Development, Center for Computational Toxicology and Exposure
Colleen M. Elonen: U.S. Environmental Protection Agency, Office of Research and Development, Center for Computational Toxicology and Exposure
David Lyons: U.S. Environmental Protection Agency, Office of Research and Development, Center for Computational Toxicology and Exposure
Kathie L. Dionisio: U.S. Environmental Protection Agency, Office of Research and Development
M. Beth Horton: Oak Ridge Associated Universities
Katherine A. Phillips: U.S. Environmental Protection Agency, Office of Research and Development, Center for Computational Toxicology and Exposure

DOI: https://doi.org/10.1038/s41597-025-05240-0
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 8

Abstract

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Abstract Since the initial release of the Chemical and Products Database (CPDat) in 2018, the United States Environmental Protection Agency has added a considerable amount of chemical exposure-related information to the database and has expanded its schema to accommodate new types of data. This data descriptor provides information regarding the structure and types of data contained within CPDat (both existing and new), new controlled vocabularies implemented to harmonize terminology across the different data types, application of a rigorous data curation and quality assurance tracking system, and various methods of accessing CPDat.

Published in Scientific Data

ISSN: 2052-4463 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/sdata/

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