The genetic basis and fitness consequences of sperm midpiece size in deer mice

Heidi S. Fisher; Emily Jacobs-Palmer; Jean-Marc Lassance; Hopi E. Hoekstra

doi:10.1038/ncomms13652

Nature Communications (Dec 2016)

The genetic basis and fitness consequences of sperm midpiece size in deer mice

Heidi S. Fisher,
Emily Jacobs-Palmer,
Jean-Marc Lassance,
Hopi E. Hoekstra

Affiliations

Heidi S. Fisher: Department of Organismic & Evolutionary Biology, Department of Molecular & Cellular Biology, Museum of Comparative Zoology, Howard Hughes Medical Institute, Harvard University
Emily Jacobs-Palmer: Department of Organismic & Evolutionary Biology, Department of Molecular & Cellular Biology, Museum of Comparative Zoology, Howard Hughes Medical Institute, Harvard University
Jean-Marc Lassance: Department of Organismic & Evolutionary Biology, Department of Molecular & Cellular Biology, Museum of Comparative Zoology, Howard Hughes Medical Institute, Harvard University
Hopi E. Hoekstra: Department of Organismic & Evolutionary Biology, Department of Molecular & Cellular Biology, Museum of Comparative Zoology, Howard Hughes Medical Institute, Harvard University

DOI: https://doi.org/10.1038/ncomms13652
Journal volume & issue: Vol. 7, no. 1
pp. 1 – 9

Abstract

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Across species there are large changes in sperm morphology, yet how and why is unclear. Here, the authors show in Peromyscus mice, that the sperm midpiece length influences swimming speed and male fertility, and is regulated by cell-type specific expression of a ubiquitously expressed gene, Prkar1a.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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