Frontiers in Cardiovascular Medicine (Oct 2022)

Occluded vein as a predictor for complications in non-infectious transvenous lead extraction

  • Anat Milman,
  • Anat Milman,
  • Eran Leshem,
  • Eran Leshem,
  • Eias Massalha,
  • Eias Massalha,
  • Karen Jia,
  • Amit Meitus,
  • Saar Kariv,
  • Yuval Shafir,
  • Yuval Shafir,
  • Michael Glikson,
  • Michael Glikson,
  • David Luria,
  • David Luria,
  • Avi Sabbag,
  • Avi Sabbag,
  • Roy Beinart,
  • Roy Beinart,
  • Eyal Nof,
  • Eyal Nof

DOI
https://doi.org/10.3389/fcvm.2022.1016657
Journal volume & issue
Vol. 9

Abstract

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BackgroundThe use of cardiovascular implantable electronic device (CIED) is steadily increasing, and complications include venous occlusion and fractured leads. Transvenous lead extraction (TLE) can facilitate the re-implantation of new leads.AimsThis study aims to explore predictors and complications of non-infectious TLE.MethodsThis study involves a retrospective analysis and comparison of characteristics, complications, and outcomes of patients with and without occluded veins (OVs) undergoing TLE at our center.ResultsIn total, eighty-eight patients underwent TLE for non-infectious reasons. Indications for TLE were lead malfunction (62; 70.5%) and need for CIED upgrade (22; 25%). Fourteen patients referred due to lead malfunction had an OV observed during venography. The OV group (36 patients) were significantly older (65.7 ± 14.1 vs. 53.8 ± 15.9, p = 0.001) and had more comorbidities. Ejection fraction (EF) was significantly lower for the OV group (27.5 vs. 57.5%, p = 0.001) and had a longer lead dwelling time (3,226 ± 2,324 vs. 2,191 ± 1,355 days, p = 0.012). Major complications were exclusive for the OV group (5.5% vs. none, p = 0.17), and most minor complications occurred in the OV group as well (33.3 vs. 4.1%, p < 0.001). Laser sheath and mechanical tools for TLE were frequently used for OV as compared to the non-occluded group (94.4 vs. 73.5%, respectively, p = 0.012). Procedure success was higher in the non-occluded group compared to the OV group (98 vs. 83.3%, respectively, p = 0.047). Despite these results, periprocedural mortality was similar between groups.ConclusionAmong the TLE for non-infectious reasons, vein occlusion appears as a major predictor of complex TLE tool use, complications, and procedural success. Venography should be considered prior to non-infectious TLE to identify high-risk patients.

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