Monitoring of the Immune Response of Pregnant Ewes and their Offsprings Following the Vaccination of the Dams with Peste Des Petits Ruminants Attenuated Vaccine (75/1)

Abstract

Assessment of the neutralizing antibody response to the attenuated strain of peste des petits ruminants Nigerian strain (75/1) in 5 pregnant ewes revealed a geometric mean titre of 194, four weeks post Vaccination. Such an appreciably high titre was found to be dropped to 73.5, throughout 48 hours post parturn. Suckling kids born to these dams passively acquired a titre of 84.5 throughout their first month of life that dropped to 48.5 at the age of 2 months. At their 5th month of age their immune titre was found to be only 4. Data generated from this study might be of value in launching vaccination campaigns against peste des petits ruminants disease.

Keywords

• monitoring; immune; response; pregnant ewes; vaccination; dams; vaccine (75/1); peste des petits ruminants