Prognostic Value of the Neutrophil–Lymphocyte and Platelet– Lymphocyte Ratios in Predicting One-Year Mortality in Patients with Hip Fractures and Aged Over 60 Years

Abstract

Aim: In this study, we aimed to determine the effect of neutrophil–lymphocyte ratio (NLR) and platelet–lymphocyte ratio (PLR) on one-year mortality in patients with hip fractures and aged over 60 years.Materials and Methods:The S72.00, S72.10, and S72.20 codes were screened according to International Classification of Disease-10, and 560 patients were included as cases of hip fractures. Blood counts on admission and clinical data were obtained from medical data. Predictors of one-year mortality were evaluated.Results: In total, 116 out of 560 patients (20.7%) included in the study died during the one-year follow-up. When the patients’ characteristics were compared according to one-year mortality (survivor and non-survivor groups), significant differences were detected for age, lymphocyte count, NLR, and PLR (p<0.05). When a Cox regression model was created to assess the factors predicting one-year mortality, the hazard ratios of NLR and PLR were 1.059 (1.022–1.097, p=0.002) and 0.997 (0.994–0999, p=0.01), respectively.Conclusion:In the study, in predict mortality among patients aged over 60 years and who had hip fractures, the NLR and PLR were observed to be higher in the survivor group than in the non-survivor group. However, when the specificity of these values is considered, it is obvious that they are not sufficiently reliable for clinical use.

Keywords

• Hip fracture
• neutrophil–lymphocyte ratio
• platelet–lymphocyte ratio
• one-year mortality