Comparison of Myocardial Infarction Frequency in Normal and Late Period Populations After Carbon Monoxide Poisoning

Abstract

Aim:Carbon monoxide (CO) poisoning is still an important factor in the rate of emergency visits. For this reason, we aimed to compare the incidence of myocardial infarction (MI) late after discharge of CO poisoning and its types as compared with the normal population.Materials and Methods:A total of 1369 patients with a diagnosis of CO intoxication and 1617 patients without a history of cardiac disease who were admitted to the emergency department between January 2005 and December 2010 were included in the study. Patients with a COHb level above 10% and the control group was followed up for 60 months for MI. The patients were divided into three groups: inferior, anterior, and non-ST elevation MI.Results:At the end of sixty months of follow-up, MI was determined in 103 (7.52%) of the CO group and 61 (3.77%) of the control group. When both groups were considered together, a significant relationship was found with gender, mortality, diabetes, hypertension, and use of tobacco products. However, when the CO group was evaluated sequentially, it was seen that it was only associated with gender, mortality, and MI types. MI groups were statistically significant with other variables except gender. In univariate and multivariate linear regression analyses, age, COHb, Tn level, and CO exposure time was found to cause increased mortality and risk of MI. After follow-up, inferior MI and mortality were higher in the patient group, and anterior MI and mortality were higher in the control group.Conclusion:Acute COHb and Tn levels may be important values in defining the risk of late MI development in patients discharged after CO poisoning.

Keywords

• carbon monoxide poisoning
• emergency department
• late-period myocardial infarction