Recent advancements in the synthesis of fused thienopyridines and their therapeutic applications

Abstract

Fused thienopyridines represent a class of heterocyclic molecules that have garnered increasing attention due to their unique structural features and versatile chemical properties. This review systematically examines the latest synthetic methodologies employed in preparing fused thienopyridine derivatives, emphasizing innovative approaches that contribute to structural diversity. Moreover, the discussion extends to the broad spectrum of therapeutic applications that fused thienopyridines offer, encompassing their utility in different diseases. The review explores the pharmacological activities and biological properties of fused thienopyridines, shedding light on their role in drug discovery and development. By offering a comprehensive overview of recent advancements in both the chemical synthesis and therapeutic applications of fused thienopyridines, this review will serve as a valuable resource for researchers and practitioners navigating the evolving landscape of medicinal chemistry.

Keywords

• Friedländer reaction
• Gould-Jacobs reaction
• Antibacterial
• Cytotoxic
• Anti-viral
• Antiplatelet