The dynamic properties of a nuclear coactivator binding domain are evolutionarily conserved

Elin Karlsson; Frieda A. Sorgenfrei; Eva Andersson; Jakob Dogan; Per Jemth; Celestine N. Chi

doi:10.1038/s42003-022-03217-y

Communications Biology (Mar 2022)

The dynamic properties of a nuclear coactivator binding domain are evolutionarily conserved

Elin Karlsson,
Frieda A. Sorgenfrei,
Eva Andersson,
Jakob Dogan,
Per Jemth,
Celestine N. Chi

Affiliations

Elin Karlsson: Department of Medical Biochemistry and Microbiology, Uppsala University
Frieda A. Sorgenfrei: Department of Medical Biochemistry and Microbiology, Uppsala University
Eva Andersson: Department of Medical Biochemistry and Microbiology, Uppsala University
Jakob Dogan: Department of Medical Biochemistry and Microbiology, Uppsala University
Per Jemth: Department of Medical Biochemistry and Microbiology, Uppsala University
Celestine N. Chi: Department of Medical Biochemistry and Microbiology, Uppsala University

DOI: https://doi.org/10.1038/s42003-022-03217-y
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 11

Abstract

Read online

Reconstruction of an ancient nuclear coactivator binding domain (NCBD) of CREB-binding protein from a bilaterian animal ancestor living 600 million years ago reveals conserved dynamic properties in human NCBD.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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