SARS-CoV-2 Omicron variant is attenuated for replication in a polarized human lung epithelial cell model

Abstract

Human alveolar epithelial lentivirus immortalized cells are very permissive for human coronaviruses and influenza A viruses, provided a suitable model for such infections of the lower respiratory tract as shown by reduced propagation of the SARS-CoV-2 Omicron variant.