Nature Communications (Aug 2022)

ROR2 regulates self-renewal and maintenance of hair follicle stem cells

  • Anthony Veltri,
  • Christopher M. R. Lang,
  • Gaia Cangiotti,
  • Chim Kei Chan,
  • Wen-Hui Lien

DOI
https://doi.org/10.1038/s41467-022-32239-7
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 17

Abstract

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Wnt signaling functions in tissue homeostasis and tumorigenesis. Here the authors show that ROR2, a Wnt receptor, plays roles not only in transducing Wnt signaling, but also in regulation of DNA damage response critical for stem cell maintenance.