Nature Communications (Jan 2016)

Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68

  • Mikael Feracci,
  • Jaelle N. Foot,
  • Sushma N. Grellscheid,
  • Marina Danilenko,
  • Ralf Stehle,
  • Oksana Gonchar,
  • Hyun-Seo Kang,
  • Caroline Dalgliesh,
  • N. Helge Meyer,
  • Yilei Liu,
  • Albert Lahat,
  • Michael Sattler,
  • Ian C. Eperon,
  • David J. Elliott,
  • Cyril Dominguez

DOI
https://doi.org/10.1038/ncomms10355
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 12

Abstract

Read online

Sam68 and T-STAR are members of the STAR family of proteins, which regulate various aspects of RNA metabolism. Here, the authors reveal structural features required for alternative splicing regulation by these proteins.