Nature Communications (Nov 2021)

NRG1/ErbB signalling controls the dialogue between macrophages and neural crest-derived cells during zebrafish fin regeneration

  • Béryl Laplace-Builhé,
  • Audrey Barthelaix,
  • Said Assou,
  • Candice Bohaud,
  • Marine Pratlong,
  • Dany Severac,
  • Gautier Tejedor,
  • Patricia Luz-Crawford,
  • Mai Nguyen-Chi,
  • Marc Mathieu,
  • Christian Jorgensen,
  • Farida Djouad

DOI
https://doi.org/10.1038/s41467-021-26422-5
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 14

Abstract

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Some fish can regenerate appendages by formation of a structure called the blastema. Here, the authors use single-cell RNA sequencing to characterize the cells required for blastema formation and fin regeneration and identified neural crest cells that orchestrate regeneration via the NRG1/ErbB axis