The emerging applications and advancements of Raman spectroscopy in pediatric cancers

Chenbei Li; Chenbei Li; Chengyao Feng; Chengyao Feng; Ruiling Xu; Ruiling Xu; Buchan Jiang; Buchan Jiang; Lan Li; Yu He; Chao Tu; Chao Tu; Zhihong Li; Zhihong Li

doi:10.3389/fonc.2023.1044177

Frontiers in Oncology (Feb 2023)

The emerging applications and advancements of Raman spectroscopy in pediatric cancers

Chenbei Li,
Chenbei Li,
Chengyao Feng,
Chengyao Feng,
Ruiling Xu,
Ruiling Xu,
Buchan Jiang,
Buchan Jiang,
Lan Li,
Yu He,
Chao Tu,
Chao Tu,
Zhihong Li,
Zhihong Li

Affiliations

Chenbei Li: Hunan Key Laboratory of Tumor Models and Individualized Medicine, The Second Xiangya Hospital, Central South University, Changsha, China
Chenbei Li: Department of Orthopaedics, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China
Chengyao Feng: Hunan Key Laboratory of Tumor Models and Individualized Medicine, The Second Xiangya Hospital, Central South University, Changsha, China
Chengyao Feng: Department of Orthopaedics, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China
Ruiling Xu: Hunan Key Laboratory of Tumor Models and Individualized Medicine, The Second Xiangya Hospital, Central South University, Changsha, China
Ruiling Xu: Department of Orthopaedics, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China
Buchan Jiang: Hunan Key Laboratory of Tumor Models and Individualized Medicine, The Second Xiangya Hospital, Central South University, Changsha, China
Buchan Jiang: Department of Orthopaedics, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China
Lan Li: Department of Pathology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China
Yu He: Department of Radiology, Second Xiangya Hospital of Central South University, Changsha, Hunan, China
Chao Tu: Hunan Key Laboratory of Tumor Models and Individualized Medicine, The Second Xiangya Hospital, Central South University, Changsha, China
Chao Tu: Department of Orthopaedics, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China
Zhihong Li: Hunan Key Laboratory of Tumor Models and Individualized Medicine, The Second Xiangya Hospital, Central South University, Changsha, China
Zhihong Li: Department of Orthopaedics, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China

DOI: https://doi.org/10.3389/fonc.2023.1044177
Journal volume & issue: Vol. 13

Abstract

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Although the survival rate of pediatric cancer has significantly improved, it is still an important cause of death among children. New technologies have been developed to improve the diagnosis, treatment, and prognosis of pediatric cancers. Raman spectroscopy (RS) is a non-destructive analytical technique that uses different frequencies of scattering light to characterize biological specimens. It can provide information on biological components, activities, and molecular structures. This review summarizes studies on the potential of RS in pediatric cancers. Currently, studies on the application of RS in pediatric cancers mainly focus on early diagnosis, prognosis prediction, and treatment improvement. The results of these studies showed high accuracy and specificity. In addition, the combination of RS and deep learning is discussed as a future application of RS in pediatric cancer. Studies applying RS in pediatric cancer illustrated good prospects. This review collected and analyzed the potential clinical applications of RS in pediatric cancers.

Published in Frontiers in Oncology

ISSN: 2234-943X (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: https://www.frontiersin.org/journals/oncology/

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