Journal of Applied Botany and Food Quality (Dec 2012)

Ochratoxin A-induced cytotoxicity in liver (HepG2) cells: Impact of serum concentration, dietary antioxidants and glutathione-modulating compounds

  • C. Bösch-Saadatmandi,
  • C. Hundhausen,
  • L. Jofre-Monseny,
  • R. Blank,
  • S. Wolffram,
  • G. Rimbach

Journal volume & issue
Vol. 80, no. 2

Abstract

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Abbrevations: BSO, buthionine sulfoximine; CAT, catechin; DMSO, dimethyl sulfoxide; DTNB, dithio-bis-nitrobenzoic acid; EGCG, epigallocatechin gallate; FCS, foetal calf serum; GSH, glutathione; IARC, international agency for research on cancer; NAC, N-acetylcysteine; NO, nitric oxide; NR, neutral red; OATP, organic anion-transporting polypeptide; OTA, ochratoxin A; PBS, phosphate buffered saline; QUE, quercetin; ROS, reactive oxygen species; ROSAC, rosmarinic acid; RPMI, roswell park memorial institute; α-TOC, α-tocopherol; α-TOC-P, α-tocopherol phosphate