Palladium-Catalyzed C–H Arylation of 1,2,3-Triazoles

Chengwei Zhang; Lin You; Chuo Chen

doi:10.3390/molecules21101268

Molecules (Sep 2016)

Palladium-Catalyzed C–H Arylation of 1,2,3-Triazoles

Chengwei Zhang,
Lin You,
Chuo Chen

Affiliations

Chengwei Zhang: Department of Biochemistry, UT Southwestern Medical Center, Dallas, TX 75390, USA
Lin You: Department of Biochemistry, UT Southwestern Medical Center, Dallas, TX 75390, USA
Chuo Chen: Department of Biochemistry, UT Southwestern Medical Center, Dallas, TX 75390, USA

DOI: https://doi.org/10.3390/molecules21101268
Journal volume & issue: Vol. 21, no. 10
p. 1268

Abstract

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Palladium(II) acetate, in combination with triphenylphosphine, catalyzes direct arylation of 1,4-disubstituted 1,2,3-triazoles effectively. This C–H arylation reaction provides facile access to fully substituted triazoles with well-defined regiochemistry.

Published in Molecules

ISSN: 1420-3049 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Chemistry: Organic chemistry
Website: http://www.mdpi.com/journal/molecules

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Abstract

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