The contribution of observational studies in supporting the WHO ‘treat all’ recommendation for HIV/AIDS

Nathan Ford; Martina Penazzato; Marco Vitoria; Meg Doherty; Mary-Ann Davies; Elizabeth Zaniewski; Olga Tymejczyk; Matthias Egger; Denis Nash

Journal of Virus Eradication (Nov 2018)

The contribution of observational studies in supporting the WHO ‘treat all’ recommendation for HIV/AIDS

Nathan Ford,
Martina Penazzato,
Marco Vitoria,
Meg Doherty,
Mary-Ann Davies,
Elizabeth Zaniewski,
Olga Tymejczyk,
Matthias Egger,
Denis Nash

Affiliations

Nathan Ford: Department of HIV and Global Hepatitis Programme, WHO, Geneva, Switzerland; Corresponding author: Nathan Ford, Department of HIV and Global Hepatitis Programme, WHO, Geneva, Switzerland
Martina Penazzato: Department of HIV and Global Hepatitis Programme, WHO, Geneva, Switzerland
Marco Vitoria: Department of HIV and Global Hepatitis Programme, WHO, Geneva, Switzerland
Meg Doherty: Department of HIV and Global Hepatitis Programme, WHO, Geneva, Switzerland
Mary-Ann Davies: Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, South Africa
Elizabeth Zaniewski: Institute of Social and Preventive Medicine, University of Bern, Switzerland
Olga Tymejczyk: Institute for Implementation Science in Population Health, City University of New York, NY, USA; Graduate School of Public Health and Health Policy, City University of New York, NY, USA
Matthias Egger: Institute of Social and Preventive Medicine, University of Bern, Switzerland
Denis Nash: Institute for Implementation Science in Population Health, City University of New York, NY, USA; Graduate School of Public Health and Health Policy, City University of New York, NY, USA

Journal volume & issue: Vol. 4
pp. 5 – 8

Abstract

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In 2015, the World Health Organization (WHO) recommended that all people living with HIV (PLWH) should start antiretroviral therapy (ART) irrespective of clinical or immune status. This recommendation followed almost 20 years of research into the clinical and population-level benefits and risks of starting ART early compared with deferring treatment. This article summarises the ways in which observational data support the work of WHO, including the support provided by the International epidemiology Databases to Evaluate AIDS (IeDEA), taking the example of ‘treat all’.

Published in Journal of Virus Eradication

ISSN: 2055-6640 (Print); 2055-6659 (Online)
Publisher: Elsevier
Country of publisher: United Kingdom
LCC subjects: Science: Microbiology; Medicine: Public aspects of medicine
Website: https://www.journals.elsevier.com/journal-of-virus-eradication

About the journal