Clinical significance of plasma-free amino acids and tryptophan metabolites in patients with non-small cell lung cancer receiving PD-1 inhibitor: a pilot cohort study for developing a prognostic multivariate model

• Akihiko Kawahara,
• Tetsuro Sasada,
• Koichi Azuma,
• Hidenobu Ishii,
• Norikazu Matsuo,
• Takaaki Tokito,
• Tomoaki Hoshino,
• Yohei Miyagi,
• Huihui Xiang,
• Tomoyuki Tagami,
• Rika Kasajima,
• Yumiko Kato,
• Sachise Karakawa,
• Shinya Kikuchi,
• Akira Imaizumi,
• Kenta Murotani

Affiliations

Akihiko Kawahara

Department of Diagnostic Pathology, Kurume University Hospital, Kurume, Japan

Tetsuro Sasada

Division of Cancer Immunotherapy, Kanagawa Cancer Center Research Institute, Yokohama, Japan

Koichi Azuma

Division of Respirology, Neurology, and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Kurume, Japan

Hidenobu Ishii

Division of Respirology, Neurology, and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Kurume, Japan

Norikazu Matsuo

Division of Respirology, Neurology, and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Kurume, Japan

Takaaki Tokito

Division of Respirology, Neurology, and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Kurume, Japan

Tomoaki Hoshino

Division of Respirology, Neurology, and Rheumatology Department of Internal Medicine, Kurume University School of Medicine, Kurume, Japan

Yohei Miyagi

Molecular Pathology and Genetics Division, Kanagawa Cancer Center Research Institute, Yokohama, Japan

Huihui Xiang

Molecular Pathology and Genetics Division, Kanagawa Cancer Center Research Institute, Yokohama, Japan

Tomoyuki Tagami

Research Institute for Bioscience Products and Fine Chemicals, Ajinomoto Co Inc, Kawasaki, Japan

Rika Kasajima

Molecular Pathology and Genetics Division, Kanagawa Cancer Center Research Institute, Yokohama, Japan

Yumiko Kato

Research Institute for Bioscience Products and Fine Chemicals, Ajinomoto Co Inc, Kawasaki, Japan

Sachise Karakawa

Research Institute for Bioscience Products and Fine Chemicals, Ajinomoto Co Inc, Kawasaki, Japan

Shinya Kikuchi

Research Institute for Bioscience Products and Fine Chemicals, Ajinomoto Co Inc, Kawasaki, Japan

Akira Imaizumi

Research Institute for Bioscience Products and Fine Chemicals, Ajinomoto Co Inc, Kawasaki, Japan

Kenta Murotani

Biostatistics Center, Kurume University School of Medicine, Kurume, Japan