Frontiers in Cellular and Infection Microbiology (Dec 2012)

Omics strategies for revealing Yersinia pestis virulence

  • Ruifu eYang,
  • Zongmin eDu,
  • Yanping eHan,
  • Lei eZhou,
  • Yajun eSong,
  • Dongsheng eZhou,
  • Yujun eCui

DOI
https://doi.org/10.3389/fcimb.2012.00157
Journal volume & issue
Vol. 2

Abstract

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Omics has remarkably changed the way we investigate and understand life. Omics differs from traditional hypothesis-driven research because it is a discovery-driven approach. Mass datasets produced from omics-based studies require experts from different fields to reveal the salient features behind these data. In this review, we summarize omics-driven studies to reveal the virulence features of Yersinia pestis through genomics, trascriptomics, proteomics, interactomics, etc. These studies serve as foundations for further hypothesis-driven research and help us gain insight into Yersinia pestis pathogenesis.

Keywords