Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease (Apr 2024)
Pharmacological Inhibition of Succinyl Coenzyme A:3‐Ketoacid Coenzyme A Transferase Alleviates the Progression of Diabetic Cardiomyopathy
- Amanda A. Greenwell,
- Seyed Amirhossein Tabatabaei Dakhili,
- Cory S. Wagg,
- Christina T. Saed,
- Jordan S.F. Chan,
- Kunyan Yang,
- Indiresh A. Mangra‐Bala,
- Magnus J. Stenlund,
- Farah Eaton,
- Keshav Gopal,
- Jason R.B. Dyck,
- Gary D. Lopaschuk,
- John R. Ussher
Affiliations
- Amanda A. Greenwell
- Faculty of Pharmacy and Pharmaceutical Sciences University of Alberta Edmonton AB Canada
- Seyed Amirhossein Tabatabaei Dakhili
- Faculty of Pharmacy and Pharmaceutical Sciences University of Alberta Edmonton AB Canada
- Cory S. Wagg
- Cardiovascular Research Institute University of Alberta Edmonton AB Canada
- Christina T. Saed
- Faculty of Pharmacy and Pharmaceutical Sciences University of Alberta Edmonton AB Canada
- Jordan S.F. Chan
- Faculty of Pharmacy and Pharmaceutical Sciences University of Alberta Edmonton AB Canada
- Kunyan Yang
- Faculty of Pharmacy and Pharmaceutical Sciences University of Alberta Edmonton AB Canada
- Indiresh A. Mangra‐Bala
- Faculty of Pharmacy and Pharmaceutical Sciences University of Alberta Edmonton AB Canada
- Magnus J. Stenlund
- Faculty of Pharmacy and Pharmaceutical Sciences University of Alberta Edmonton AB Canada
- Farah Eaton
- Faculty of Pharmacy and Pharmaceutical Sciences University of Alberta Edmonton AB Canada
- Keshav Gopal
- Faculty of Pharmacy and Pharmaceutical Sciences University of Alberta Edmonton AB Canada
- Jason R.B. Dyck
- Cardiovascular Research Institute University of Alberta Edmonton AB Canada
- Gary D. Lopaschuk
- Cardiovascular Research Institute University of Alberta Edmonton AB Canada
- John R. Ussher
- Faculty of Pharmacy and Pharmaceutical Sciences University of Alberta Edmonton AB Canada
- DOI
- https://doi.org/10.1161/JAHA.123.032697
- Journal volume & issue
-
Vol. 13,
no. 7
Abstract
No abstracts available.Keywords
- diabetic cardiomyopathy
- diastolic function
- ketone metabolism
- succinyl CoA:3‐ketoacid CoA transferase
- type 2 diabetes