Association of eNOS T786C genetic polymorphism with the risk of aneurysmal subarachnoid haemorrhage

Abstract

Unruptured intracranial aneurysms (IAs) are increasingly detected due to advancements in neuroimaging. Despite improvements in treatment, aneurysmal subarachnoid haemorrhage (aSAH) is associated with high mortality and morbidity. Treatment decisions for IA are complex and individualized, considering aneurysm and patient-related risk factors. Genetic factors, particularly endothelial nitric oxide synthase (eNOS) polymorphisms, have been implicated in IA formation and rupture risk.

Keywords

• aneurysm
• subarachnoid haemorrhage
• enos
• polymorphism