EFFECTS OF NON-INHERITED PARENTAL HLA-ANTIGENS UPON IMMUNE RESPONSE IN PROGENY

Abstract

Abstract. In pregnancy, mutual cell exchange proceeds between mother and foetus. Therefore, a great research interest is connected with phenomenon of specific influence of non-inherited parental HLA upon various immune reactions in the offspring. This article deals with possible mechanisms of influence of non-inherited parental HLA upon development of immunocompetence in foetus and child, including examples from transplantation, autoimmune pathology, and partial immunodefiencies.

Keywords

• non-inherited parental hla
• immune response
• transplantation
• autoimmunity
• vaccination