Bulletin of the Chemical Society of Ethiopia (Dec 2005)

<b>Antimicrobial diterpenoid alkaloids from <i>Erythrophleum suaveolens</i> (Guill. & perr.) Brenan</b>

  • F.N. Ngounou,
  • R.N. Manfouo,
  • L.A. Tapondjou,
  • D. Lontsi,
  • V. Kuete,
  • V. Penlap,
  • F.X. Etoa,
  • M-A.L. Dubois,
  • B.L. Sondengam

Journal volume & issue
Vol. 19, no. 2
pp. 221 – 226

Abstract

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An investigation of the stem bark of Erythrophleum suaveolens (Guill. & Perr.) Brenan yielded the known amide norcassaide (1) and a new diterpenoid alkaloid named norerythrosuaveolide (2) which was characterized as 7β-hydroxy-7-deoxo-6-oxonorcassaide. The structures were established on the basis of one and two-dimensional 1H and 13C NMR spectral data. The compounds showed potent antimicrobial activities against bacteria and yeasts.

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