Journal of Nepal Medical Association (Sep 2021)

Metronidazole Induced Cerebellar Toxicity: A Case Report

  • Shova Sapkota,
  • Aliska Niroula,
  • Rina Prajapati,
  • Subhani Sharma,
  • Krishna Dhungana

DOI
https://doi.org/10.31729/jnma.6644
Journal volume & issue
Vol. 59, no. 241

Abstract

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Metronidazole is a widely used antibiotic against bacterial and protozoan infections. Even though the therapeutic use of the drug is high, it is associated with some severe side effects like neurotoxicity such as optic neuropathy, peripheral neuropathy, encephalopathy and cerebellar toxicity. We present a case of a 55-years male presented with dysarthria, who had positive cerebellar sign and magnetic resonance imaging findings suggestive of metronidazole induced cerebellar toxicity following metronidazole therapy for two months in a case of liver abscess. And, the symptoms resolved after cessation of metronidazole.

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