Evaluations of Auto-Focusing Methods under a Microscopic Imaging Modality for Metaphase Chromosome Image Analysis

Yuchen Qiu; Xiaodong Chen; Yuhua Li; Wei R. Chen; Bin Zheng; Shibo Li; Hong Liu

doi:10.3233/ACP-130077

Analytical Cellular Pathology (Jan 2013)

Evaluations of Auto-Focusing Methods under a Microscopic Imaging Modality for Metaphase Chromosome Image Analysis

Yuchen Qiu,
Xiaodong Chen,
Yuhua Li,
Wei R. Chen,
Bin Zheng,
Shibo Li,
Hong Liu

Affiliations

Yuchen Qiu: Center for Bioengineering and School of Electrical and Computer Engineering, University of Oklahoma, Norman, OK, USA
Xiaodong Chen: Center for Bioengineering and School of Electrical and Computer Engineering, University of Oklahoma, Norman, OK, USA
Yuhua Li: Center for Bioengineering and School of Electrical and Computer Engineering, University of Oklahoma, Norman, OK, USA
Wei R. Chen: Department of Engineering and Physics, University of Central Oklahoma, Edmond, OK, USA
Bin Zheng: Department of Radiology, University of Pittsburgh, Pittsburgh, PA, USA
Shibo Li: Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA
Hong Liu: Center for Bioengineering and School of Electrical and Computer Engineering, University of Oklahoma, Norman, OK, USA

DOI: https://doi.org/10.3233/ACP-130077
Journal volume & issue: Vol. 36, no. 1-2
pp. 37 – 44

Abstract

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Background: Auto-focusing is an important operation in high throughput imaging scanning. Although many auto-focusing methods have been developed and tested for a variety of imaging modalities, few investigations have been performed on the selection of an optimal auto-focusing method that is suitable for the pathological metaphase chromosome analysis under a high resolution scanning microscopic system.

Published in Analytical Cellular Pathology

ISSN: 2210-7177 (Print); 2210-7185 (Online)
Publisher: Hindawi Limited
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens; Science: Biology (General): Cytology
Website: https://www.hindawi.com/journals/acp/

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