International Medical Case Reports Journal (Jun 2016)
Upper eyelid granuloma: a rare delayed-onset complication secondary to cosmetic filler injection on forehead
Abstract
Shu-I Pao,1 Shih-Min Lin,1,2 Yun-Hsiang Chang,1 Shang-Yi Chiang,1 1Department of Ophthalmology, Tri-Service General Hospital, National Defense Medical Center, Taipei, 2Department of Ophthalmology, Kaohsiung Armed Forces General Hospital, Kaohsiung Abstract: A 72-year-old Taiwanese woman had the history of cosmetic cryopreserved autologous fat injection on her forehead ~21 years ago and was referred to our oculoplastic clinic and presented with multiple painless mass, which she had for 4 years, on both upper eyelids. Histopathology confirmed the diagnosis of foreign body granuloma on both upper eyelids. Clinicians should be aware of the potential complication of granuloma reaction and migration even many years after the injection. We advise that autologous fat injection should be performed solely by trained physicians and it should be made known that there is a possible occurrence of migration. Keywords: upper eyelid granuloma, cosmetic filler, excisional biopsy
