Endocrine Regulations (Oct 2020)

Insulin receptor substrate 1 gene expression is strongly up-regulated by HSPB8 silencing in U87 glioma cells

  • Hnatiuk Oksana S.,
  • Tsymbal Dariia O.,
  • Minchenko Dmytro O.,
  • Khita Olena O.,
  • Viletska Yulia M.,
  • Rundytska Olha V.,
  • Kozynkevych Halyna E.,
  • Maslak Hanna S.,
  • Minchenko Oleksandr H.

DOI
https://doi.org/10.2478/enr-2020-0026
Journal volume & issue
Vol. 54, no. 4
pp. 231 – 243

Abstract

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Objective. The aim of the present investigation was to study the expression of genes encoding IRS1 (insulin receptor substrate 1) and some other functionally active proteins in U87 glioma cells under silencing of polyfunctional chaperone HSPB8 for evaluation of the possible significance of this protein in intergenic interactions.

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