Rho-dependent transcription termination proceeds via three routes

Eunho Song; Heesoo Uhm; Palinda Ruvan Munasingha; Seungha Hwang; Yeon-Soo Seo; Jin Young Kang; Changwon Kang; Sungchul Hohng

doi:10.1038/s41467-022-29321-5

Nature Communications (Mar 2022)

Rho-dependent transcription termination proceeds via three routes

Eunho Song,
Heesoo Uhm,
Palinda Ruvan Munasingha,
Seungha Hwang,
Yeon-Soo Seo,
Jin Young Kang,
Changwon Kang,
Sungchul Hohng

Affiliations

Eunho Song: Department of Physics and Astronomy, and Institute of Applied Physics, Seoul National University
Heesoo Uhm: Department of Physics and Astronomy, and Institute of Applied Physics, Seoul National University
Palinda Ruvan Munasingha: Department of Biological Sciences, Korea Advanced Institute of Science and Technology
Seungha Hwang: Department of Chemistry, Korea Advanced Institute of Science and Technology
Yeon-Soo Seo: Department of Biological Sciences, Korea Advanced Institute of Science and Technology
Jin Young Kang: Department of Chemistry, Korea Advanced Institute of Science and Technology
Changwon Kang: Department of Biological Sciences, Korea Advanced Institute of Science and Technology
Sungchul Hohng: Department of Physics and Astronomy, and Institute of Applied Physics, Seoul National University

DOI: https://doi.org/10.1038/s41467-022-29321-5
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 12

Abstract

Read online

Rho is a general transcription termination factor in bacteria. Here, Song et al. use single-molecule fluorescence assays to provide evidence that Rho-mediated transcription termination can occur via three kinetically different routes.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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